John Murdoch awakens alone in a strange hotel to find that he has lost his memory and is wanted for a series of brutal and bizarre murders. While trying to piece together his past, he stumbles upon a fiendish underworld controlled by a group of beings known as The Strangers who possess the ability to put people to sleep and alter the city and its inhabitants. Now Murdoch must find a way to stop them before they take control of his mind and destroy him.

An adult nicknamed Misty is narrating a story about one summer in his life when he was an adolescent in the late 1960s. He was living in a Catholic orphanage in the Australian outback. His best mates were the "December boys" - Maps, Spark and Spit - the four of them so named because they were the boys in the orphanage born in the month of December. With a recent windfall, the orphanage decided to give each of the boys a group vacation for each of their birthdays, the December boys the first to...